{"created":"2023-05-15T12:12:47.675590+00:00","id":685,"links":{},"metadata":{"_buckets":{"deposit":"1dc78cfd-f4be-41ee-bac8-caca60b27301"},"_deposit":{"created_by":1,"id":"685","owners":[1],"pid":{"revision_id":0,"type":"depid","value":"685"},"status":"published"},"_oai":{"id":"oai:kansai-u.repo.nii.ac.jp:00000685","sets":["63:69"]},"author_link":["1820","1814","1817","1811","1816","1819","1815","1812","1813"],"control_number":"685","item_9_alternative_title_20":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Measurement of Erythrocyte Deformability by Uniaxial Stretching : Mesurement of Apparent Young's Modulus and Time Constant of Shape Recovering","subitem_alternative_title_language":"en"}]},"item_9_biblio_info_7":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2015","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"7","bibliographicPageStart":"1","bibliographicVolumeNumber":"53","bibliographic_titles":[{"bibliographic_title":"生体医工学"}]}]},"item_9_description_4":{"attribute_name":"概要","attribute_value_mlt":[{"subitem_description":"An erythrocyte can be deformed very easily by even small amounts of stress, enabling it to flow smoothly through approximately 3μm diameter microvessels despite its larger size of 8μm in diameter and 2μm in thickness. Reduction of erythrocyte deformability leads to poor circulation particularly in microvessels, which may result in hypertension and various circulatory diseases. To clarify blood microcirculatory properties, it is very important to understand the deformability of erythrocytes. However, a standard method for quantitative evaluation of erythrocyte deformability has not yet been established. In this study, an apparent Young's modulus and a time constant for the recovery of erythrocyte shape following uniaxial stretching are proposed as deformability indices. When an erythrocyte was pulled horizontally on opposite ends using two micropipettes, tensile stress and strain were measured, and an apparent Young's modulus was calculated based on Hooke's law. On returning to its initial shape after the erythrocyte was released from stretching, the elapsed time and strain were measured, and a time constant for shape recovery was calculated based on the Kelvin model. The average apparent Young's modulus was 16.0 Pa, and the average time constant was 113.4 ms, with a slight tendency toward an inverse relation between the two physical quantities.","subitem_description_type":"Other"}]},"item_9_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"1816","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Khori, Shimpei"}]},{"nameIdentifiers":[{"nameIdentifier":"1817","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Kato, Yousuke"}]},{"nameIdentifiers":[{"nameIdentifier":"1819","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yamamoto, Yasufumi"}]},{"nameIdentifiers":[{"nameIdentifier":"1820","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Bando, Kiyoshi"}]}]},"item_9_publisher_34":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"一般社団法人 日本生体医工学会"}]},"item_9_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11633569","subitem_source_identifier_type":"NCID"}]},"item_9_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1347443X","subitem_source_identifier_type":"PISSN"}]},"item_9_version_type_17":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"郡, 慎平","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"加藤, 陽介","creatorNameLang":"ja"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"田地川, 勉","creatorNameLang":"ja"},{"creatorName":"Tajikawa, Tsutomu","creatorNameLang":"en"}],"familyNames":[{"familyName":"田地川","familyNameLang":"ja"},{"familyName":"Tajikawa","familyNameLang":"en"}],"givenNames":[{"givenName":"勉","givenNameLang":"ja"},{"givenName":"Tsutomu","givenNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[{"affiliationNameIdentifier":"","affiliationNameIdentifierScheme":"ISNI","affiliationNameIdentifierURI":"http://www.isni.org/isni/"}],"affiliationNames":[{"affiliationName":"","affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"山本, 恭史","creatorNameLang":"ja"},{"creatorName":"Yamamoto, Yasuhumi","creatorNameLang":"en"}],"familyNames":[{"familyName":"山本","familyNameLang":"ja"},{"familyName":"Yamamoto","familyNameLang":"en"}],"givenNames":[{"givenName":"恭史","givenNameLang":"ja"},{"givenName":"Yasuhumi","givenNameLang":"en"}],"nameIdentifiers":[{},{}]},{"creatorNames":[{"creatorName":"板東, 潔","creatorNameLang":"ja"}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-05-20"}],"displaytype":"detail","filename":"KU-1100-20150000-00.pdf","filesize":[{"value":"5.6 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"KU-1100-20150000-00.pdf","url":"https://kansai-u.repo.nii.ac.jp/record/685/files/KU-1100-20150000-00.pdf"},"version_id":"5f1efd15-4100-4db6-b539-b81c35101123"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"erythrocyte","subitem_subject_scheme":"Other"},{"subitem_subject":"deformability","subitem_subject_scheme":"Other"},{"subitem_subject":"uniaxial stretching","subitem_subject_scheme":"Other"},{"subitem_subject":"apparent Young's modulus","subitem_subject_scheme":"Other"},{"subitem_subject":"time constant.","subitem_subject_scheme":"Other"},{"subitem_subject":"平成25～26年度関西大学若手研究者育成経費","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"jpn"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"研究 単軸引張によるヒト赤血球の変形能の測定 : 見かけのヤング率と形状回復時定数の測定","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"研究 単軸引張によるヒト赤血球の変形能の測定 : 見かけのヤング率と形状回復時定数の測定","subitem_title_language":"ja"}]},"item_type_id":"9","owner":"1","path":["69"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2015-04-22"},"publish_date":"2015-04-22","publish_status":"0","recid":"685","relation_version_is_last":true,"title":["研究 単軸引張によるヒト赤血球の変形能の測定 : 見かけのヤング率と形状回復時定数の測定"],"weko_creator_id":"1","weko_shared_id":-1},"updated":"2023-11-22T01:49:45.257360+00:00"}