@article{oai:kansai-u.repo.nii.ac.jp:00023353,
 author = {Yamai, Yu-suke and Tanaka, Akio and Yajima, Tatsuo and Ishida, Kyoji and Natsutani, Itaru and Uesato, Shinichi and Nagaoka, Yasuo and Sumiyoshi, Takaaki},
 issue = {1},
 journal = {Heterocycles},
 month = {Dec},
 note = {Using a novel tandem reduction-cyclization, we synthesized t-butyl 3-alkyloxindole-3-carboxylates from the di-t-butyl 2-alkyl-2-(2-nitrophenyl)malonate. Introduction of an α-substituent to the di-t-butyl 2-(2-nitrophenyl)-malonates and addition of acid promoted reactivity. This methodology was successfully applied to gram-scale-synthesis of the t-butyl 3-methyloxindole-3-carboxylate 1 and 3-hydroxymethyl-3-methyloxindole 2 without silica gel column chromatography., Part of this work was supported by the Kansai University Subsidy for Supporting Young Scholars, 2015 “Development of macrocyclization reaction via a photoaffinity reaction”, JSPS KAKENHI Grant Number 15K18903, Grant-in-Aid for Young Scientists (B) – Japan and MEXT – Supported Program for the Strategic Research Foundation at Private Universities (2013–2017) – Japan., 2015年度関西大学若手研究者育成経費},
 pages = {192--210},
 title = {SYNTHESIS OF SUBSTITUTED t-BUTYL 3-ALKYLOXINDOLE-3-CARBOXYLATES FROM DI-t-BUTYL (2-NITROPHENYL)MALONATES},
 volume = {97},
 year = {2017}
}