| アイテムタイプ |
学術雑誌論文 / Journal Article(1) |
| 公開日 |
2025-11-20 |
| タイトル |
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タイトル |
Exploring animal protein sources against prevent age-related short-term memory decline in mice: Dietary fish (Alaska Pollock) protein exhibits superior protective effects |
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言語 |
en |
| 言語 |
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言語 |
eng |
| 資源タイプ |
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資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
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資源タイプ |
journal article |
| アクセス権 |
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アクセス権 |
open access |
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アクセス権URI |
http://purl.org/coar/access_right/c_abf2 |
| 著者 |
細見, 亮太
村上, 由希
村上, 大和
西本, 彩乃
田中, 元稀
木村 貴博
今村, 行雄
吉田, 宗弘
福永, 健治
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| 概要 |
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内容記述タイプ |
Other |
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内容記述 |
Dietary factors, particularly proteins, have been extensively explored to combat cognitive impairment. We have previously reported that dietary fish (Alaska Pollock) protein (APP) is more effective than casein (CAS) or fish oil in maintaining short-term memory in senescence-accelerated mice prone 10 (SAMP10). To examine the specificity of the protective effect of APP intakes against short-term memory decline, we assessed the impact of various dietary animal proteins, including APP, CAS, chicken breast protein (CP), and whey pro- tein (WP), against age-related cognitive function in SAMP10 mice. After feeding the experimental diets for five months, memory was assessed using the Y-maze. The APP group exhibited a significant increase in spontaneous alternation behav- ior as an indicator of working memory when group compared with groups fed with other protein source. Additionally, the APP group displayed significantly higher neurofilament heavy chain positivity than the CAS and CP groups, as evidenced immunohistochemical analysis. Gut microbiota analysis indicated that dietary APP significantly enhanced the relative abundance of Lactobacillus, which positively correlated with spontaneous alternation behavior. Collectively, these findings suggest that dietary APP is more effective than CAS, CP, or WP in preventing age-related short-term memory decline and morphological abnor- malities in the hippocampal axons of SAMP10 mice. Moreover, APP-mediated improvements in cognitive deficits may be associated with changes in microbiota diversity. |
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言語 |
en |
| 書誌情報 |
en : JOURNAL OF FOOD SCIENCE
巻 89,
号 6,
p. 3776-3787,
発行日 2024-05-20
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| ISSN |
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収録物識別子タイプ |
PISSN |
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収録物識別子 |
0022-1147 |
| ISSN |
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収録物識別子タイプ |
EISSN |
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収録物識別子 |
1750-3841 |
| 書誌レコードID |
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収録物識別子タイプ |
NCID |
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収録物識別子 |
AA00698289 |
| DOI |
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関連タイプ |
isVersionOf |
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識別子タイプ |
DOI |
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関連識別子 |
https://doi.org/10.1111/1750-3841.17119 |
| 権利 |
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権利情報 |
This is the peer reviewed version of the following article: Murakami, Y., Hosomi, R., Murakami, H., Nishimoto, A., Tanaka, G., Kimura, T., Imamura, Y., Yoshida, M., & Fukunaga, K. (2024). Exploring animal protein sources against prevent age-related short-term memory decline in mice: Dietary fish (Alaska Pollock) protein exhibits superior protective effects. Journal of Food Science, 89, 3776–3787, which has been published in final form at https://doi.org/10.1111/1750-3841.17119. This article may be used for non-commercial purposes in accordance with Wiley Terms and Conditions for Use of Self-Archived Versions. This article may not be enhanced, enriched or otherwise transformed into a derivative work, without express permission from Wiley or by statutory rights under applicable legislation. Copyright notices must not be removed, obscured or modified. The article must be linked to Wiley’s version of record on Wiley Online Library and any embedding, framing or otherwise making available the article or pages thereof by third parties from platforms, services and websites other than Wiley Online Library must be prohibited. |
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言語 |
en |
| 著者版フラグ |
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出版タイプ |
AM |
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出版タイプResource |
http://purl.org/coar/version/c_ab4af688f83e57aa |
| 出版者 |
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出版者 |
Wiley |
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言語 |
en |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
animal protein |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
demyelination |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
fish protein |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
scence-accelerated mouse prone 10 |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
short-term memory |
| キーワード |
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言語 |
ja |
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主題Scheme |
Other |
|
主題 |
関西大学 |
| キーワード |
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言語 |
en |
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主題Scheme |
Other |
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主題 |
Kansai University |
KU-1100-20240520-01.pdf (3.1 MB)
