@article{oai:kansai-u.repo.nii.ac.jp:00011149,
 author = {大谷, 英之 and 関, 眞佐子 and Sugihara-Seki , Masako},
 issue = {5},
 journal = {ながれ},
 month = {Oct},
 note = {微小血管内では,血管壁近傍に赤血球がほとんど通らない領域が見られ,血漿層と呼ばれている.本研究では,細静脈壁に接着している白血球に血流が及ぼす剪断応力に対して,血漿層が与える影響をモデル解析によって調べた.血管を直円管,白血球を剛体球とし,血液の流れを血漿層と,赤血球が多数通過する中心層とからなる二層流と仮定して白血球周りの流れ場を数値的に解析した.その結果として,血漿層の効果によって白血球に作用する剪断応力は増加することが示された.
\nThe blood flow past a leukocyte adhered to the microvessel wall is analyzed by a numerical simulation, taking the presence of a cell-free layer into account. The adherent leukocyte is modeled as a sphere attached to the wall of a circular cylindrical tube. The blood flow is modeled as a two-phase flow, consisting of a plasma flow in a cell-free layer adjacent to the vessel wall and the cell-rich flow in the central region of the vessel. It is assumed that each fluid in both regions is Newtonian with a uniform viscosity and that the viscosity of the cell-free layer is smaller than that of the central core. The interface between the two regions is assumed to be parallel to the streamlines. Numerical simulations by a finite element method have demonstrated that there are two different cases of the flow pattern around a sphere: one is a case where the whole sphere is embedded in the cell-free layer, and the other is a case where the sphere is covered by the central core. In both cases, the maximum magnitudes of the shear stress acting on the leukocyte are higher than those in the absence of the cell-free layer.},
 pages = {363--371},
 title = {円管内壁に接着している球形粒子周りの遅い流れ : 二層流モデルによる数値解析},
 volume = {29},
 year = {2010}
}