2026-03-10T22:19:42Z https://kansai-u.repo.nii.ac.jp/oai

oai:kansai-u.repo.nii.ac.jp:00011526 2023-05-15T18:29:19Z 528:1588:1595:1597

Measurement of Chiral Recognition Properties of Crown Ethers Using Matrix Assisted Laser Desorption Ionization Mass Spectrometry Sawada, Masami 26944 Harada, Manabu 26945 Takai, Yoshio 26946 Nakano, Kazurou 26947 Kuroda, Masao 26948 Arakawa, Ryuichi 26949 MALDI mass spectrometry Chiral recognition Chiral crown ether Amino acid ester Deuterium labeling Cyclofructan Host-guest complex Non-covalent chiral Hydrogen bonding host-guest complex ions between chiral crown ethers and chiral amino acid ester salts, detected by matrix assisted laser desorption ionization (MALDI) mass spectrometry (MS) with a DHBA or MSA matrix, were studied on the view point of chiral recognition properties of the chiral crown hosts. The chiral recognition property (IR/IS-dn value≅1.0) obtained by the present MALDI-MS is sharply different from the IR/IS-dn value obtained by FAB-MS or ESI-MS (≠1.0) in the same host-guest combinations. The direct comparison on the basis of the IR/IS-dn values suggests that MALDI-MS is not a suitable measurement tool for chiral host-guest interactions probably because of the particular way of sample preparation involving a crystallization process. journal article Mass Spectrometry Society of Japan 2000 VoR application/pdf Journal of the Mass Spectrometry Society of Japan 2 48 141 144 AA1254271X 13408097 https://kansai-u.repo.nii.ac.jp/record/11526/files/KU-1100-20000000-10.pdf http://hdl.handle.net/10112/5989 https://kansai-u.repo.nii.ac.jp/records/11526 eng 10.5702/massspec.48.141